Author

P. Kakade

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Shaw· 2 shared A. Waddell· 2 shared H. Ojha· 2 shared M. Muqit· 2 shared R. Bayliss· 2 shared T. Macartney· 2 shared A. A. Mishra· 1 shared A. J. Whitworth· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersBiochemistry

A. Shaw

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Regulation of Human PINK1 ubiquitin kinase by Serine167, Serine228 and Cysteine412 phosphorylation

A. Waddell, H. Ojha, S. Agarwal, C. Clarke, A. Terriente-Felix, H. Zhou, P. Kakade, A. Knebel, A. Shaw, R. Gourlay, J. Varghese, R. Soares, R. Toth, T. Macartney, P. Eyers, , M. Muqit

This study identifies phosphorylation sites in hPINK1 that regulate its activation and ubiquitin interaction, revealing a novel inhibitory mechanism involving pCys412.

bioRxiv · Mar 31, 2023 · PreprintBiochemistry

Mapping of a N-terminal α-helix domain required for human PINK1 stabilisation, Serine228 autophosphorylation and activation in cells

P. Kakade, H. Ojha, O. Raimi, A. Shaw, A. Waddell, J. Ault, S. Burel, K. Brockmann, A. Kumar, M. Ahanger, E. Krysztofinska, T. Macartney, R. Bayliss, J. C. Fitzgerald, M. Muqit

This study identifies an N-terminal α-helix domain in PINK1 critical for its stabilization, autophosphorylation, and activation, linking mutations in this region to Parkinson's disease.

bioRxiv · Sep 6, 2021Biochemistry

Candida albicans Isolates 529L and CHN1 Exhibit Stable Colonization of the Murine Gastrointestinal Tract

L. McDonough, A. A. Mishra, N. Tosini, P. Kakade, S. Penumutchu, S.-H. Liang, C. Maufrais, B. Zhai, Y. Taur, P. Belenky, R. J. Bennett, T. J. Hohl, A. Y. Koh, I. V. Ene

This study identifies two Candida albicans isolates that stably colonize the murine gastrointestinal tract, revealing strain-specific differences in colonization and host antimicrobial peptide sensitivity.

bioRxiv · Jun 27, 2021Microbiology