Author

S. Burel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1 Organism:human· 1

Frequent Co-Authors

A. Lesage· 2 shared C. Marionneau· 2 shared D. Maloney· 2 shared J. M. Nerbonne· 2 shared M. Lorenzini· 2 shared M. Muqit· 2 shared R. R. Townsend· 2 shared A. Kumar· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPhysiology

A. Lesage

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Author profile →

4 papers

Recent·Most cited

Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain

E. Bagnoli, Y.-E. Lin, S. Burel, E. Jaimon, O. Antico, C. Themistokleous, J. Nikoloff, I. Morella, J. Watzlawik, F. Fiesel, W. Springer, F. Tonelli, S. Brooks, S. Dunnett, R. Brambilla, , M. Muqit

This study shows LRRK2 and PINK1 function in parallel neuroprotective pathways affecting ciliogenesis in Parkinson's disease, suggesting shared therapeutic targets.

bioRxiv · Jun 11, 2024Biochemistry

FHF2 phosphorylation and regulation of native myocardial NaV1.5 channels

A. Lesage, M. Lorenzini, S. Burel, M. Sarlandie, F. Bibault, D. Maloney, J. Silva, R. R. Townsend, J. M. Nerbonne, C. Marionneau

This study identifies phosphorylation sites on FHF2 in mouse NaV1.5 channels and shows differential regulation of neonatal and adult ventricular NaV1.5 by FHF2 phosphorylation.

bioRxiv · Jan 31, 2023Physiology

Mapping of a N-terminal α-helix domain required for human PINK1 stabilisation, Serine228 autophosphorylation and activation in cells

P. Kakade, H. Ojha, O. Raimi, A. Shaw, A. Waddell, J. Ault, S. Burel, K. Brockmann, A. Kumar, M. Ahanger, E. Krysztofinska, T. Macartney, R. Bayliss, J. C. Fitzgerald, M. Muqit

This study identifies an N-terminal α-helix domain in PINK1 critical for its stabilization, autophosphorylation, and activation, linking mutations in this region to Parkinson's disease.

bioRxiv · Sep 6, 2021Biochemistry

Proteomic and functional mapping of cardiac NaV1.5 channel phosphorylation reveals multisite regulation of surface expression and gating

M. Lorenzini, S. Burel, A. Lesage, E. Wagner, C. Charriere, P.-M. Chevillard, B. Evrard, D. Maloney, K. M. Ruff, R. V. Pappu, S. Wagner, J. M. Nerbonne, J. R. Silva, R. R. Townsend, L. S. Maier, C. Marionneau

The paper identifies 42 phosphorylation sites on NaV1.5 channels in mouse hearts and shows their roles in regulating channel expression and gating.

bioRxiv · Apr 29, 2020Physiology