Author

J. Borleis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:optimal transport· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:Drosophila· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

D. S. Pal· 3 shared P. N. Devreotes· 2 shared T. Banerjee· 2 shared Y. Lin· 2 shared C. Janetopoulos· 1 shared C.-H. Huang· 1 shared G. Qin· 1 shared H. Zhan· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiochemistry

D. S. Pal

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Self-organizing glycolytic waves fuel cell migration and cancer progression

H. Zhan, D. S. Pal, J. Borleis, C. Janetopoulos, C.-H. Huang, P. N. Devreotes

The paper shows that glycolytic waves in the cell cortex drive migration and cancer progression by providing ATP for morphological events and correlating with metastatic potential.

bioRxiv · Jan 28, 2024Biochemistry

Ras-mediated homeostatic control of front-back signaling dictates cell polarity

Y. Lin, D. S. Pal, P. Banerjee, T. Banerjee, G. Qin, Y. Deng, J. Borleis, P. A. Iglesias, P. Devreotes

This study uses optogenetics to show that RasGAPs regulate cell polarity by enhancing actomyosin contractility at the back and F-actin polymerization at the front.

bioRxiv · Aug 30, 2023Cell Biology

Direct activation of the Ras-Akt network mediates polarity and organizes protrusions in human neutrophil migration

D. S. Pal, T. Banerjee, Y. Lin, J. Borleis, P. N. Devreotes

This study shows that local activation of the Ras-Akt network in human neutrophils directly controls cell polarity and migration by regulating protrusions and motility.

bioRxiv · Oct 27, 2022Immunology