P. Banerjee

A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist

The paper identifies PLSCR1 as a host factor restricting SARS-CoV-2 entry, which recent variants have evolved to bypass, through a CRISPR screen and integration of genetic studies.

Complementary Cytoskeletal Feedback Loops Control Signal Transduction Excitability and Cell Polarity

This study identifies cytoskeletal feedback loops that regulate Ras/PI3K signaling and cell polarity in Dictyostelium and neutrophils by modulating actin and myosin dynamics.

The unseen invaders: tracking phylogeographic dynamics and genetic diversity of cryptic Pomacea canaliculata and P. maculata (Golden Apple Snails) across Taiwan

This study tracks the phylogeographic dynamics and genetic diversity of invasive golden apple snails in Taiwan to inform management strategies.

A translation proofreader of archaeal origin imparts multialdehyde stress tolerance to land plants

This study shows that the archaeal DTD2 enzyme protects plants from aldehyde toxicity by removing harmful adducts on tRNA, and its overexpression enhances aldehyde resistance in Arabidopsis.

Molecular dynamics simulations of HIV-1 matrix-membrane interactions at different stages of viral maturation

This study uses molecular dynamics simulations to analyze how HIV-1 matrix protein interactions with lipids change during viral maturation, identifying altered binding modes of PIP2 lipids.

Cooperative Membrane Binding of HIV-1 Matrix Proteins

This study investigates the membrane binding dynamics of HIV-1 MA protein trimers and their interactions with anionic phospholipids using molecular dynamics simulations.

Ras-mediated homeostatic control of front-back signaling dictates cell polarity

This study uses optogenetics to show that RasGAPs regulate cell polarity by enhancing actomyosin contractility at the back and F-actin polymerization at the front.

Conformational transitions of the HIV-1 Gag polyprotein upon multimerization and gRNA binding

This study uses molecular dynamics simulations to investigate how HIV-1 Gag polyprotein conformation changes during multimerization and gRNA binding, revealing structural transitions and their functional implications.

Functional loss of rffG and rfbB, encoding dTDP-glucose 4,6-dehydratase, changes colony morphology, cell shape, motility and virulence in Salmonella Typhimurium

This study shows that deleting both rffG and rfbB in Salmonella Typhimurium causes changes in cell shape, motility, and virulence.

Single-cell RNA sequencing identifies response of renal lymphatic endothelial cells to acute kidney injury

This study uses single-cell RNA sequencing to characterize renal lymphatic endothelial cells' response to acute kidney injury and identifies gene expression changes across different injury models.

Piezo1 as a force-through-membrane sensor in red blood cells.

This study investigates Piezo1 distribution and dynamics in red blood cells, finding it preferentially localizes to the dimple and exhibits curvature coupling behavior.

Antibiotic induced biofilm formations in Pseudomonas aeruginosa strains KPW.1-S1 and HRW.1-S3 are associated with increased production of eDNA and exoproteins, increased ROS generation, and increased cell surface hydrophobicity

This study shows that gentamicin increases biofilm formation in Pseudomonas aeruginosa strains by boosting eDNA, exoproteins, ROS, and cell surface hydrophobicity.

Nanotopography modulates intracellular excitable systems through cytoskeleton actuation

The paper shows nanotopography is sensed directly by cytoskeletal networks, with implications for texture sensing and guidance cues in microenvironments.

Diversity of Secretion System Apparatus in Tomato Wilt Causing Ralstonia solanacearum Strains: a Comparative Analysis Using in-silico Approach

The paper uses an in-silico approach to analyze secretion system components in five Ralstonia solanacearum strains, identifying conserved and horizontally transferred systems.

Nano-hydroxyapatite coating synthesized on quasi-fibrillar superstructures of collagen hydrolysate leads to superior osteoblast proliferation when compared to nano-hydroxyapatite synthesized on collagen fibrils

This paper compares nano-hydroxyapatite coatings synthesized on collagen hydrolysate and collagen fibrils, finding that the former supports better osteoblast proliferation due to improved structural and chemical properties.

Contribution of quasi-fibrillar superstructures in peroxide quenching by collagen peptides derived from fish processing by-products and their application as natural food additives

This study identifies collagen peptides' quasi-fibrillar structures as effective in quenching peroxides and extending oil shelf life, with applications as natural food additives.

Generation of glucocorticoid resistant SARS-CoV-2 T-cells for adoptive cell therapy

The paper expands SARS-CoV-2 T-cells from COVID-19 donors using IL-2/4/7 cytokines, achieving >1000-fold expansion with preserved function, and inactivates the glucocorticoid receptor to create glucocorticoid-resistant T-cells for adoptive therapy.

Inhibition of the av integrin-TGF-b axis improves natural killer cell function against glioblastoma stem cells

The paper shows that inhibiting the integrin-TGF-β axis enhances NK cell function against glioblastoma stem cells, suggesting it as a therapeutic target.

CIS checkpoint deletion enhances the fitness of cord blood derived natural killer cells transduced with a chimeric antigen receptor

This paper combines CIS checkpoint deletion with CAR engineering in NK cells to enhance their metabolic fitness and anti-tumor activity in a lymphoma model.