J. Brooks

CRISPR screens and lectin microarrays identify novel high mannose N-glycan regulators

The paper uses CRISPR screens and lectin microarrays to identify TM9SF3 and the CCC complex as novel regulators of high mannose N-glycan synthesis.

Assessing changes in global fire regimes

This study assesses changes in global fire regimes using expert opinions, finding increased fire regime change rates and future intensification under higher emission scenarios.

Testing the effect of oxytocin on social grooming in bonobos

This study tests if oxytocin increases social grooming in bonobos, finding an overall increase but limited individual effects.

Longitudinal preclinical imaging characterization of drug delivery potential after radiotherapy in the healthy and leukemic bone marrow vascular microenvironment

This study uses longitudinal multiphoton imaging to assess how radiotherapy affects drug delivery in the bone marrow vasculature of healthy and leukemic mice.

The periphery is the dominant site of B-cell deletion in a polyclonal repertoire

The paper investigates B-cell tolerance in a polyclonal repertoire, finding that anergy, not deletion, dominates in the periphery despite self-antigen exposure.

Development of Kinetic Modeling to Assess Multi-functional Vascular Response to Low Dose Radiation in Leukemia

The paper uses intravital multiphoton microscopy to assess vascular parameters in a leukemia mouse model and shows radiation therapy improves drug uptake.