Author

J. Buer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Günther· 2 shared A. M. Westendorf· 2 shared A. Westendorf· 2 shared B. Kleuser· 2 shared E. Gulbins· 2 shared F. Schumacher· 2 shared M. Hose· 2 shared W. Hansen· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

A. Günther

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell-intrinsic ceramides determine T cell function during melanoma progression

M. Hose, A. Günther, E. Naser, F. Schumacher, T. Schönberger, J. Falkenstein, A. Papadamakis, B. Kleuser, K. A. Becker, E. Gulbins, A. Haimovitz-Friedman, J. Buer, A. Westendorf, W. Hansen

This study shows that ceramide levels in T cells affect their function during melanoma progression, with reduced ceramide impairing T cell responses and elevated ceramide enhancing cytotoxic activity.

bioRxiv · Aug 31, 2022Immunology

The acid ceramidase/ceramide axis controls parasitemia in Plasmodium yoelii-infected mice by regulating erythropoiesis

A. Günther, M. Hose, F. Schumacher, B. Kleuser, K. Matuschewski, K. S. Lang, E. Gulbins, J. Buer, A. Westendorf, W. Hansen

This study shows that acid ceramidase deficiency reduces parasitemia in Plasmodium yoelii-infected mice by impairing erythropoiesis and T cell responses.

bioRxiv · Mar 8, 2022Microbiology

DJ-1 depletion slows down immunoaging in T-cell compartments

N. Zeng, C. Capelle, A. Baron, S. Cire, C. Leonard, D. Coowar, H. Koseki, A. M. Westendorf, J. Buer, D. Brenner, R. Krüger, R. Balling, M. Ollert, F. Q. Hefeng

This study shows that DJ-1 depletion delays immunoaging in T-cell compartments in both humans and mice by preserving non-senescent T cells and affecting hematopoietic and naive-CD8-intrinsic mechanisms.

bioRxiv · May 21, 2021Immunology

Independent human mesenchymal stromal cell-derived extracellular vesicle preparations differentially affect symptoms in an advanced murine Graft-versus-Host-Disease model

R. J. Madel, V. Börger, R. Dittrich, M. Bremer, T. Tertel, N. Ngo Thi Phuong, H. A. Babo, L. Kordelas, J. Buer, P. A. Horn, A. M. Westendorf, S. Brandau, C. J. Kirschning, B. Giebel

The paper shows that different human MSC-derived EV preparations have varying therapeutic effects in a murine GvHD model, emphasizing the need for potency evaluation before clinical use.

bioRxiv · Dec 21, 2020 · PreprintCell Biology