Author

C. Capelle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

M. Ollert· 4 shared N. Zeng· 4 shared R. Balling· 4 shared A. Baron· 3 shared C. Leonard· 3 shared D. Coowar· 3 shared D. Brenner· 2 shared E. Danileviciute· 2 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

M. Ollert

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

DJ-1 depletion slows down immunoaging in T-cell compartments

N. Zeng, C. Capelle, A. Baron, S. Cire, C. Leonard, D. Coowar, H. Koseki, A. M. Westendorf, J. Buer, D. Brenner, R. Krüger, R. Balling, M. Ollert, F. Q. Hefeng

This study shows that DJ-1 depletion delays immunoaging in T-cell compartments in both humans and mice by preserving non-senescent T cells and affecting hematopoietic and naive-CD8-intrinsic mechanisms.

bioRxiv · May 21, 2021Immunology

FAM13A regulates KLRG1 expression and interferon gamma production of natural killer cells

N. Zeng, M. Theresine, C. Capelle, N. Patil, C. Masquelier, C. Davril, A. Baron, D. Coowar, X. Dervillez, A. Poli, C. Leonard, R. Balling, M. Ollert, J. Zimmer, F. Q. Hefeng

This study shows that FAM13A depletion increases KLRG1 and reduces IFN-gamma production in NK cells, leading to increased lung metastases in a mouse model.

bioRxiv · Aug 26, 2020 · PreprintImmunology

Identification of VIMP as a gene inhibiting cytokine production in human CD4+ effector T cells

C. Capelle, N. Zeng, E. Danileviciute, S. F. Rodrigues, M. Ollert, R. Balling, F. Q. He

The paper identifies VIMP as a gene inhibiting cytokine production in human CD4+ effector T cells through E2F5 and Ca2+/NFATC2 pathways using a network-guided approach.

bioRxiv · Jul 6, 2020Immunology

PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis

E. Danileviciute, N. Zeng, C. Capelle, N. Paczia, M. A. Gillespie, H. Kurniawan, D. Coowar, D. Vogt-Weisenhorn, G. Gomez-Giro, M. Grusdat, A. Baron, C. Guerin, D. G. Franchina, C. Leonard, O. Domingues, , F. Q. He

This study shows PARK7/DJ-1 enhances PDH activity in Tregs by inhibiting PDHA phosphorylation, maintaining Treg homeostasis and reducing EAE severity.

bioRxiv · Dec 20, 2019Biochemistry

Homeostatic and Interferon-induced gene expression represent different states of promoter-associated transcription factor ISGF3

E. Platanitis, D. Demiroz, C. Capelle, A. Schneller, M. Hartl, T. Gossenreiter, M. Mueller, M. Novatchkova, T. Decker

The paper shows that interferons switch macrophages from resting to gene expression by altering ISGF3 subunit composition, with IFNγ inducing full ISGF3 complex formation on DNA.

bioRxiv · Jul 25, 2018 · PreprintImmunology