Author

J. C. Javitt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:rat· 1

Frequent Co-Authors

M. Manyak· 1 shared M. T. Sapko· 1 shared R. Kumar· 1 shared R. Panicucci· 1 shared R. Siegel· 1 shared W. Jordan· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 6 mutual co-author links

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1 shared paperMicrobiology

M. Manyak

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJan 14, 2024

NRX-101 (D-Cycloserine + Lurasidone) , a Qualified Infectious Disease Product, is Active Against Drug-Resistant Urinary Pathogens In Vitro

M. T. Sapko, M. Manyak, R. Panicucci, J. C. Javitt

This study evaluates NRX-101, a combination of D-Cycloserine and lurasidone, against drug-resistant urinary pathogens in vitro, showing DCS's antibacterial activity and lurasidone's lack of interference.

DOI 10.1101/2024.01.14.575572

experimental assay

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivJun 18, 2022

NRX-101, A RAPID-ACTING ANTI-DEPRESSANT, DOES NOT CAUSE NEUROTOXICITY FOLLOWING KETAMINE ADMINISTRATION IN PRECLINICAL MODELS

W. Jordan, R. Siegel, R. Kumar, J. C. Javitt

This study evaluates the neurotoxicity of NRX-101 (D-cycloserine/lurasidone) with and without ketamine in rats, finding no histologic neurotoxicity even at maximum doses.

DOI 10.1177/10915818231176971

ratexperimental assay

𝕏 PostBluesky