Pharmacology & ToxicologybioRxiv
Molecular Basis for G-protein-Coupled Receptor (GPCR) Activation and Biased Signalling at the Platelet Thrombin Receptor Proteinase Activated Receptor-4 (PAR4)
P. Thibeault, J. C. LeSarge, D. Arends…·R. Ramachandran
This study identifies molecular determinants of PAR4 activation and biased signaling by analyzing peptide agonists and their interactions with the receptor.
DOI 10.1074/jbc.ra119.011461