Cell BiologybioRxiv
Molecular basis of mitotic decline during human aging
J. C. Macedo, S. Vaz, B. Bakker…·E. Logarinho
This study identifies aneuploidy as a driver of mitotic decline in aging by showing FoxM1 repression leads to chromosome segregation defects and senescence.
DOI 10.1038/s41467-018-05258-6