Author

P. Bakker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

F. Foijer· 2 shared A. van den Brink· 1 shared B. Bakker· 1 shared E. Logarinho· 1 shared J. C. Macedo· 1 shared J. M. Escandell· 1 shared L. Raz· 1 shared L. Zhou· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

F. Foijer

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

CDC20 determines the sensitivity to spindle assembly checkpoint (SAC) inhibitors

S. Zheng, L. Raz, L. Zhou, Y. Cohen-Sharir, R. Tian, R. Wardenaar, M. J. C. Broekhuis, M. F. Suarez Peredo Rodriguez, S. Wobben, A. van den Brink, P. Bakker, F. Foijer, U. Ben-David

The paper identifies CDC20 expression as a determinant of sensitivity to SAC inhibitors, showing that aneuploid cells with high CDC20 levels are more sensitive to these drugs.

bioRxiv · Dec 21, 2023 · PreprintCancer Biology

Molecular basis of mitotic decline during human aging

J. C. Macedo, S. Vaz, B. Bakker, R. Ribeiro, P. Bakker, J. M. Escandell, M. G. Ferreira, R. Medema, F. Foijer, E. Logarinho

This study identifies aneuploidy as a driver of mitotic decline in aging by showing FoxM1 repression leads to chromosome segregation defects and senescence.

bioRxiv · Feb 6, 2018Cell Biology