Author

J. C. Sudar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

A. Ballesteros· 1 shared C. Mulligan· 1 shared C. R. Nisler· 1 shared D. Sauer· 1 shared D.-N. Wang· 1 shared J. J. Marden· 1 shared J. M. Lotthammer· 1 shared J. Song· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

A. Ballesteros

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2 papers

Recent·Most cited

BiophysicsbioRxivJan 11, 2022

Structural basis of ion - substrate coupling in the Na+-dependent dicarboxylate transporter VcINDY

D. Sauer, J. J. Marden, J. C. Sudar…·D.-N. Wang

This study reveals the structural mechanism by which VcINDY couples sodium and substrate binding through an induced-fit mechanism, showing that sodium binding stabilizes the substrate binding site.

DOI 10.1038/s41467-022-30406-4

bacteria (other)cryo-EM

𝕏 PostBluesky

BiophysicsbioRxivPreprintSep 17, 2021

In Silico Electrophysiology of Inner-Ear Mechanotransduction Channel TMC1 Models

S. Walujkar, J. M. Lotthammer, C. R. Nisler…·M. Sotomayor

The paper uses molecular dynamics simulations to study ion conduction in TMC1 models, revealing a peripheral permeation pathway and lipid-mediated gating mechanisms in inner-ear mechanotransduction channels.

DOI 10.1101/2021.09.17.460860

mechanistic / dynamical modelprotein folding & dynamics

𝕏 PostBluesky