BiophysicsbioRxiv
Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic
J. Cholewa-Waclaw, R. Shah, S. Webb…·A. Bird
The paper uses mathematical modeling and experimental analysis to show MeCP2 creates 'slow sites' in gene bodies, affecting RNA polymerase II traffic and gene expression.
DOI 10.1073/pnas.1903549116