The histone chaperone FACT induces Cas9 multi-turnover behavior and modifies genome manipulation in human cells
A. S. Wang, L. Chen, R. A. Wu, C. D. Richardson, B. G. Gowen, K. R. Kazane, J. T. Vu, S. K. Wyman, J. Shin, J. C. Walter, J. Corn
This study identifies FACT as a factor that influences Cas9 turnover and genome editing efficiency in human cells.
bioRxiv · Jul 23, 2019Cell Biology