Author

J. D. Tranter

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

E. E. Morrison· 2 shared J. W. Dear· 2 shared A. Lartigau· 1 shared A. Srivastava· 1 shared B. Lopez-Longarela· 1 shared C. Goldring· 1 shared D. C. Duffy· 1 shared D. M. Rissin· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

E. E. Morrison

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivJan 6, 2020

Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells

O. Matthews, E. E. Morrison, J. D. Tranter…·J. W. Dear

This study shows that hepatocyte-derived microRNA, particularly miR-122, is transferred to kidney tubular cells and regulates CYP2E1 expression, influencing drug toxicity.

DOI 10.1016/j.ebiom.2020.103092

mousebulk RNA-seq

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivPreprintSep 20, 2019

Direct detection of circulating microRNA-122 using dynamic chemical labelling with single molecule detection overcomes stability and isomiR challenges for biomarker qualification

B. Lopez-Longarela, E. E. Morrison, J. D. Tranter…·J. J. Diaz-Mochon

This paper develops a DCL assay to directly detect miR-122 in serum/plasma, overcoming stability and isomiR challenges for DILI biomarker qualification.

DOI 10.1101/777458

humanrat

𝕏 PostBluesky