Author

J. Dopfer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

M. P. Schwalm· 2 shared S. Knapp· 2 shared V. V. Rogov· 2 shared A. Kumar· 1 shared A. Stolz· 1 shared B. Kuester· 1 shared C. W. E. Tomlinson· 1 shared D. FearoniD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

M. P. Schwalm

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2 papers

Recent·Most cited

Thermodynamic Characterization of LC3/GABARAP Ligands byIsothermal Titration Calorimetry

J. Dopfer, M. P. Schwalm, S. Knapp, V. V. Rogov

This paper provides a detailed protocol for producing LIR peptides and using ITC to study their interactions with LC3/GABARAP proteins, including troubleshooting guidance.

bioRxiv · Jan 8, 2024 · PreprintBiochemistry

Targeting LC3/GABARAP for degrader development and autophagy modulation

M. P. Schwalm, J. Dopfer, A. Kumar, F. A. Greco, N. Bauer, F. Loehr, J. Heering, S. Cano, S. Lechner, T. Hanke, I. Bekic, V. Morasch, D. Fearon, P. G. Marples, C. W. E. Tomlinson, , V. V. Rogov

The paper evaluates the druggability of LC3/GABARAP for autophagy modulators and identifies ligands that bind to the HP2 pocket of the LIR docking site.

bioRxiv · Oct 5, 2023 · PreprintBiochemistry