Author

B. Kuester

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

F. Loehr· 2 shared S. Knapp· 2 shared A. Doelle· 1 shared A. Kraemer· 1 shared A. Kumar· 1 shared A. Stolz· 1 shared A.-F. Deroubaix· 1 shared B. Adhikari· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

F. Loehr

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeting LC3/GABARAP for degrader development and autophagy modulation

M. P. Schwalm, J. Dopfer, A. Kumar, F. A. Greco, N. Bauer, F. Loehr, J. Heering, S. Cano, S. Lechner, T. Hanke, I. Bekic, V. Morasch, D. Fearon, P. G. Marples, C. W. E. Tomlinson, , V. V. Rogov

The paper evaluates the druggability of LC3/GABARAP for autophagy modulators and identifies ligands that bind to the HP2 pocket of the LIR docking site.

bioRxiv · Oct 5, 2023 · PreprintBiochemistry

Design, Synthesis and Evaluation of WD-repeat containing protein 5 (WDR5) degraders

A. Doelle, B. Adhikari, A. Kraemer, J. Weckesser, N. Berner, L.-M. Berger, M. Diebold, M. Szewczyk, D. Barsyte-Lovejoy, C. Arrowsmith, J. Gerbel, F. Loehr, V. Doetsch, M. Eilers, S. Heinzlmeir, , S. Knapp

This study designs, synthesizes, and evaluates two series of WDR5 degraders, showing that linker length and nature affect degradation efficacy.

bioRxiv · Apr 12, 2021 · PreprintCancer Biology

A hetero-oligomeric remorin-receptor complex regulates plant development

N. B. Abel, C. A. Buschle, C. Hernandez-Ryes, S. S. Burkart, A.-F. Deroubaix, J. Mergner, J. Gronnier, I. K. Jarsch, J. Folgmann, K. H. Braun, E. Bayer, V. Germain, P. Derbyshire, F. L. H. Menke, B. Kemmerling, , T. Ott

The paper shows that Group 1 remorins form a hetero-oligomeric complex at the plasma membrane, recruiting RIR1 and NILR2 to regulate plant development.

bioRxiv · Jan 28, 2021 · PreprintPlant Biology