J. E. Crowe

This paper develops genetically engineered Aedes aegypti mosquitoes expressing an engineered antibody that broadly neutralizes all four DENV serotypes, significantly reducing viral transmission.

This paper demonstrates that multi-state protein design using the RECON algorithm predicts sequences optimal for conformational change, showing increased sequence conservation and resemblance to evolutionary sequence space.

The paper uses peptide arrays and bioinformatics to analyze sera from patients infected with mosquito-borne viruses, aiming to improve serodiagnostics and epitope mapping.

The paper identifies a transiently exposed epitope on influenza H7 hemagglutinin that is targeted by a potent neutralizing monoclonal antibody.