ImmunologybioRxiv
Inflammatory CD4/CD8 double positive human T cells arise from reactive CD8 T cells and are sufficient to mediate GVHD pathology
N. J. Hess, D. P. Turicek, J. Riendeau…·C. M. Capitini
This study identifies CD4+/CD8+ double positive T cells as mediators of xenogeneic GVHD but with limited GVL activity.
DOI 10.1126/sciadv.adf0567