Author

J. Eastham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Daemen· 1 shared A. K. Katakam· 1 shared A. N. Lima· 1 shared A. Pribluda· 1 shared A. Zijlstra· 1 shared B. Haley· 1 shared B. Nabet· 1 shared C. Poon· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Daemen

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Automated tumor immunophenotyping predicts clinical benefit from anti-PD-L1 immunotherapy

X. Li, J. Eastham, J. M. Giltnane, W. Zou, A. Zijlstra, E. Tabatsky, R. Banchereau, C.-W. Chang, B. Nabet, N. Patil, L. Molinero, S. Chui, M. Peterson, S. Lau, L. Rangell, , H. Koeppen

This paper develops automated tumor immunophenotyping pipelines to predict clinical benefit from anti-PD-L1 therapy in NSCLC and TNBC patients.

bioRxiv · Apr 3, 2023Pathology

G9a methyltransferase governs cell identity in the lung and is required for KRAS G12D tumor development and propagation

A. Pribluda, A. Daemen, A. N. Lima, X. Wang, M. Hafner, C. Poon, Z. Modrusan, A. K. Katakam, O. Foreman, J. Eastham, J. Hung, B. Haley, J. T. Garcia, E. L. Jackson, M. R. Junttila

This study shows G9a methyltransferase regulates Wnt signaling in lung development and tumor progression by controlling β-catenin transcriptional activity, and its inhibition prevents KrasG12D lung cancer.

bioRxiv · Apr 20, 2020 · PreprintCancer Biology