S. Lau

Genome assembly of the rare and endangered Grantham's camellia, Camellia granthamiana

This paper presents a chromosome-scale genome assembly of the rare Camellia granthamiana using PacBio and Omni-C data, providing a resource for conservation and phylogenetic studies.

An annual gene expression profile of markers for programmed cell death and polyphenols biosynthesis across heartwood forming stems in Robinia pseudoacacia

This study tracks gene expression of programmed cell death and polyphenol biosynthesis markers in Robinia pseudoacacia heartwood-forming stems over a year, revealing their correlation and regional variation.

In vivo metabolomics identifies CD38 as an emergent vulnerability in LKB1-mutant lung cancer

The paper identifies CD38 as a therapeutic target in LKB1-mutant lung cancer through in vivo metabolomics and shows that targeting CD38 inhibits tumor growth.

Automated tumor immunophenotyping predicts clinical benefit from anti-PD-L1 immunotherapy

This paper develops automated tumor immunophenotyping pipelines to predict clinical benefit from anti-PD-L1 therapy in NSCLC and TNBC patients.

Loss of the Long Non-coding RNA OIP5-AS1 Exacerbates Heart Failure in a Sex-Specific Manner

This study shows that loss of OIP5-AS1 worsens heart failure in female mice but not males, suggesting a sex-specific role in cardiac function.

A Pan-respiratory Antiviral Chemotype Targeting a Host Multiprotein Complex

The paper identifies a novel antiviral chemotype effective against multiple respiratory viruses by targeting a host multi-protein complex involved in viral lifecycle and innate immunity.

Replication of MERS and SARS coronaviruses in bat cells offers insights to their ancestral origins

This study replicates MERS and SARS coronaviruses in bat cells, finding that DPP4 expression and species-specific factors determine viral susceptibility.