Rapid Emergence and Evolution of SARS-CoV-2 Variants in Advanced HIV Infection
S. H. Ko, P. Radecki, F. Belinky, J. Bhiman, S. Meiring, J. Kleynhans, D. Amoako, V. Guerra Canedo, M. Lucas, D. Kekana, N. Martinson, L. Lebina, J. Everatt, S. Tempia, T. Bylund, , E. A. Boritz
This study shows that advanced HIV infection leads to high intra-host SARS-CoV-2 spike diversity and adaptive evolution, potentially contributing to new variants of concern.
bioRxiv · Jan 5, 2024 · PreprintMicrobiology