Author

S. Richardson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 2 Biophysics· 1 Ecology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:ecology & biodiversity· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

A. Bodenstein· 2 shared G. van den Berg· 2 shared M. Boswell· 2 shared M. van der Mescht· 2 shared P. Moore· 2 shared V. Ueckermann· 2 shared Z. de Beer· 2 shared A. J. Blumenfeld· 1 shared

Activity by Year

2016-2022 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

A. Bodenstein

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Comparative genetic study of the colony structure and colony spatial distribution between the higher termite Amitermes parvulus and the lower, subterranean termite Reticulitermes flavipes in an urban environment

P. A. Eyer, M. N. Moran, S. Richardson, P. T. Shults, K.-L. K. Liu, A. J. Blumenfeld, R. Davis, E. L. Vargo

This study compares the colony structure and spatial distribution of two termite species in an urban environment, revealing differences in breeding systems and foraging ranges.

bioRxiv · Dec 27, 2022 · PreprintEvolutionary Biology

SARS-CoV-2 BA.4 infection triggers more cross-reactive neutralizing antibodies than BA.1

S. Richardson, T. Motlou, M. van der Mescht, B. Lambson, J. Everatt, D. Amoako, A. Van Gottberg, N. Wolter, Z. de Beer, T. Roma de Villiers, A. Bodenstein, G. van den Berg, T. M. Rossouw, M. Boswell, V. Ueckermann, , P. Moore

This study compares the neutralizing antibody responses to SARS-CoV-2 BA.4 and BA.1, finding BA.4 induces more cross-reactive antibodies, suggesting potential benefits for next-generation vaccines.

bioRxiv · Jul 14, 2022 · PreprintImmunology

Fc effector activity and neutralization against SARS-CoV-2 BA.4 is compromised in convalescent sera, regardless of the infecting variant

S. Richardson, P. Kgagudi, N. P. Manamela, H. Kaldine, E. Venter, T. Pillay, B. E. Lambson, M. van der Mescht, T. Hermanus, Z. de Beer, T. de Villier, A. Bodenstein, G. van den Berg, M. du Pisanie, W. Burgers, , P. Moore

This study shows that convalescent sera and post-vaccination breakthrough infections have reduced neutralization and ADCC activity against SARS-CoV-2 BA.4, despite prior infection with different variants.

bioRxiv · Jul 14, 2022 · PreprintImmunology

Medulloblastoma Group 3 and 4 Tumors Comprise a Clinically and Biologically Significant Expression Continuum Reflecting Human Cerebellar Development

D. Williamson, E. C. Schwalbe, D. Hicks, K. A. Aldinger, J. Lindsey, S. Crosier, S. Richardson, J. Goddard, R. Hill, J. Castle, Y. Grabovska, J. Hacking, B. Pizer, S. B. Wharton, T. S. Jacques, , S. C. Clifford

The paper shows medulloblastoma Group3 and Group4 tumors form a transcriptional continuum linked to cerebellar development, with prognostic and molecular implications.

bioRxiv · Jun 9, 2022Cancer Biology

Gene expression profiling reveals B cells are highly educated by the pancreatic environment during autoimmune diabetes

J. Boldison, J. Hopkinson, J. Davies, J. Pearson, P. Leete, S. Richardson, N. G. Morgan, F. S. Wong

The paper identifies transcriptional profiles of B cell subsets in the pancreas and lymph nodes, revealing their adaptation to the diabetic environment and potential role in autoimmune diabetes.

bioRxiv · May 19, 2022 · PreprintImmunology

TLR7 ligation augments haematopoiesis in Rps14 (uS11) deficiency via paradoxical suppression of inflammatory signalling and enhanced differentiation

O. C. Pena, A. Lubin, J. Rowell, C. A. Hockings, Y. Jung, Y. Hoade, P. Dace, L. E. Valdivia, K. Tuschl, C. Böiers, M. C. Virgilio, S. Richardson, E. M. Payne

This study identifies imiquimod, a TLR7 agonist, as a therapeutic for MDS by enhancing haematopoiesis through paradoxical anti-inflammatory effects and increased differentiation.

bioRxiv · Jul 6, 2020Cancer Biology

Investigating low-velocity fluid flow in tumours using convection-MRI

S. Walker-Samuel, T. A. Roberts, R. Ramasawmy, J. Burrell, S. P. Johnson, B. Siow, S. Richardson, M. Goncalves, D. Pendse, S. P. Robinson, R. B. Pedley, M. F. Lythgoe

This study develops convection-MRI to investigate low-velocity fluid flow in tumors and shows it correlates with interstitial fluid pressure measurements in mouse models.

bioRxiv · Oct 9, 2017Biophysics

Symmetric assembly and disassembly processes in an ecological network

J. Tylianakis, L. Martinez-Garcia, S. Richardson, D. Peltzer, I. A. Dickie

The paper studies symmetrical assembly and disassembly processes in an ecological network over time, finding that species with high centrality drive network structure and nestedness.

bioRxiv · Mar 7, 2016Ecology