Single-cell transcriptomics reveals that tumor-infiltrating natural killer cells are activated by localized ablative immunotherapy and share anti-tumor signatures induced by immune checkpoint inhibitors
K. Liu, N. Sadeghipour, A. R. Hoover…·W. R. Chen
This study shows that localized ablative immunotherapy activates NK cells and shares anti-tumor gene signatures with immune checkpoint inhibitors, correlating with improved patient survival.