Author

J. Fleischmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

E. Stefan· 2 shared T. Kaserer· 2 shared A. Dodaro· 1 shared A. Feichtner· 1 shared A. Heberle· 1 shared A. Sauerwein· 1 shared B. Sprenger· 1 shared D. Bante· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiochemistry

E. Stefan

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Author profile →

2 papers

Recent·Most cited

Kinases in motion: impact of protein and small molecule interactions on kinase conformations

V. Kugler, S. Schwaighofer, A. Feichtner, F. Enzler, J. Fleischmann, S. Strich, S. Schwarz, R. Wilson, P. Tschaikner, J. Troppmair, V. Sexl, P. Meier, T. Kaserer, E. Stefan

This study uses KinCon-reporter technology to analyze conformational changes in disease-associated kinases upon drug, regulatory protein, and pathway activation interactions, revealing insights into therapeutic strategies.

bioRxiv · Jan 11, 2024Biochemistry

A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system

F. Costacurta, A. Dodaro, D. Bante, H. Schoeppe, B. Sprenger, S. A. Moghadasi, J. Fleischmann, M. Pavan, D. Bassani, S. Menin, S. Rauch, L. Krismer, A. Sauerwein, A. Heberle, T. Rabensteiner, , E. Heilmann

This study identifies and characterizes SARS-CoV-2 Mpro mutations conferring resistance to nirmatrelvir using a VSV-based system and biochemical assays.

bioRxiv · Sep 22, 2023Microbiology