Author

J. Frater

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Organism:human· 4 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

H. Brown· 3 shared M. Pace· 3 shared N. Robinson· 3 shared P. Klenerman· 3 shared S. Fidler· 3 shared C. Willberg· 2 shared E. Hopkins· 2 shared J. Fox· 2 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

H. Brown

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Gonadal androgens are associated with decreased type I interferon production by pDCs and increased IgG titres to BNT162b2 following co-vaccination with live attenuated influenza vaccine in adolescents

O. L. Sampson, C. Jay, E. Adland, A. Csala, N. Lim, S. M. Ebbrecht, L. C. Gilligan, A. E. Taylor, S. S. George, S. Longet, L. C. Jones, E. Barnes, J. Frater, P. Klenerman, S. Dunachie, , P. Goulder

The paper investigates how gonadal androgens affect type I interferon production by pDCs and IgG titres to BNT162b2 in adolescents co-vaccinated with LAIV.

bioRxiv · Aug 1, 2023 · PreprintImmunology

Expression of type I interferon-associated genes at antiretroviral therapy interruption predicts HIV virological rebound

P. Zacharopoulou, E. Marchi, A. Ogbe, N. Robinson, H. Brown, M. Jones, L. Parolini, M. Pace, N. Grayson, P. Kaleebu, H. Rees, S. Fidler, P. Goulder, P. Klenerman, J. Frater

The paper identifies type I interferon-associated gene expression in CD4 T cells as a predictor of delayed HIV viral rebound after antiretroviral therapy interruption.

bioRxiv · Nov 24, 2020 · PreprintMicrobiology

HIV reservoir size is determined prior to ART initiation and linked to CD8 T cell activation and memory expansion

G. E. Martin, M. Pace, F. Shearer, E. Zilber, J. Hurst, J. Meyerowitz, J. P. Thornhill, J. Lwanga, H. Brown, N. Robinson, E. Hopkins, N. Olejniczak, N. Nwokolo, J. Fox, S. Fidler, , CHERUB investigators

This study finds that pre-ART HIV DNA levels predict reservoir size one year after treatment initiation during primary HIV infection, linked to CD8 T cell activation and memory expansion.

bioRxiv · Mar 17, 2019Immunology

Enrichment of the HIV reservoir in CD32+ CD4 T cells occurs early in blood and tissue

G. Martin, M. Pace, J. Thornhill, C. Phetsouphanh, J. Meyerowitz, M. Gossez, E. Hopkins, H. Brown, N. Robinson, N. Olejniczak, G. Ramjee, P. Kaleebu, K. Porter, C. Willberg, P. Klenerman, , J. Frater

The paper shows HIV DNA enrichment in CD32+ CD4 T cells early in infection but finds no correlation with rebound viraemia or HIV DNA levels.

bioRxiv · Jul 27, 2017Immunology