Author

J. Gribble

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:virus· 1

Frequent Co-Authors

M. R. Denison· 3 shared A. J. Pruijssers· 2 shared L. J. Stevens· 2 shared X. Lu· 2 shared A. L. Routh· 1 shared A. S. George· 1 shared C. J. Gordon· 1 shared D. P. Porter· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersMicrobiology

M. R. Denison

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Distinct genetic determinants and mechanisms of SARS-CoV-2 resistance to remdesivir

L. J. Stevens, A. J. Pruijssers, H. W. Lee, C. J. Gordon, E. P. Tchesnokov, J. Gribble, A. S. George, T. M. Hughes, X. Lu, J. Li, J. K. Perry, D. P. Porter, T. Cihlar, T. P. Sheahan, R. S. Baric, , M. R. Denison

This study identifies distinct mutations in SARS-CoV-2's RdRp that confer remdesivir resistance, showing their biochemical mechanisms and transferability to other coronaviruses.

bioRxiv · Jan 25, 2022 · PreprintMicrobiology

Reovirus RNA recombination is sequence directed and generates internally deleted defective genome segments during passage

S. C. Smith, J. Gribble, J. R. Diller, M. A. Wiebe, T. W. Thoner, M. R. Denison, K. M. Ogden

This study shows reovirus generates internally deleted defective genome segments through sequence-directed recombination during passage, while rotavirus rarely does so.

bioRxiv · Oct 19, 2020Microbiology

The coronavirus proofreading exoribonuclease mediates extensive viral recombination

J. Gribble, A. J. Pruijssers, M. L. Agostini, J. Anderson-Daniels, J. D. Chappell, X. Lu, L. J. Stevens, A. L. Routh, M. R. Denison

This study shows that the coronavirus proofreading exoribonuclease nsp14-ExoN is essential for RNA recombination and generates defective viral genomes.

bioRxiv · Apr 23, 2020Microbiology