Author

J. Hoenderop

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Bhatta· 1 shared A. Lemoff· 1 shared A. M. van Genderen· 1 shared C. Duran· 1 shared E. A. Zaal· 1 shared E. Sendino Garvi· 1 shared F. Latta· 1 shared G. van der Slobbe· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperPhysiology

A. Bhatta

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A novel KCNJ16 kidney organoid model recapitulates the disease phenotype and shows restoration of lipid accumulation upon treatment with statins

E. Sendino Garvi, G. van der Slobbe, E. A. Zaal, J. H. F. de Baaij, J. Hoenderop, R. Masereeuw, M. J. Janssen, A. M. van Genderen

This paper develops a KCNJ16-depleted kidney organoid model to study a genetic kidney tubulopathy, showing that statin treatment reduces lipid accumulation and fibrosis.

bioRxiv · Dec 22, 2023 · PreprintCell Biology

Insulin receptor substrate 4 deficiency mediates the insulin effect on the epithelial magnesium channel TRPM6 and causes hypomagnesemia

J. Zhang, S. W. An, S. Neelam, A. Bhatta, M. Nie, C. Duran, M. Bal, F. Latta, J. S. Hou, J. J. Otto, J. Kozlitina, A. Lemoff, J. Hoenderop, M. Baum, M. T. Wolf

This paper identifies IRS4 as a novel regulator of TRPM6 channel activity and Mg2+ homeostasis, showing IRS4 mediates insulin's effect on TRPM6 phosphorylation and Mg2+ absorption.

bioRxiv · Oct 1, 2022 · PreprintPhysiology

Functional basis for calmodulation of the TRPV5 calcium channel

S. R. Roig, N. Thijssen, M. van Erp, J. Fransen, J. Hoenderop, J. van der Wijst

This study characterizes the dynamic regulation of TRPV5 by calmodulin using advanced microscopy and biochemical assays, revealing a 1:2 stoichiometry and lobe-specific interactions.

bioRxiv · Feb 16, 2021 · PreprintCell Biology