MicrobiologybioRxivPreprint
The histone methyltransferase SETD2 regulates HIV expression and latency through a post-transcriptional mechanism.
C. R. Bussey-Sutton, A. Ward, A.-M. W. Turner…·E. P. Browne
This study shows that SETD2 inhibition reduces HIV gene expression and latency by altering viral RNA splicing, not transcription.
DOI 10.1101/2023.12.15.571871