ImmunologybioRxiv
Arp2/3 complex-driven spatial patterning of the B cell receptor (BCR) enhances immune synapse formation, BCR signaling, and cell activation
M. Bolger-Munro, K. Choi, J. Scurll…·M. R. Gold
The paper shows that Arp2/3 complex-driven spatial reorganization of BCR microclusters enhances immune synapse formation, BCR signaling, and B cell activation in response to membrane-bound antigens.
DOI 10.7554/elife.44574