J. J. Schlezinger

Perfluorooctanoic Acid Induces Liver and Serum Dyslipidemia in Humanized PPARα Mice Fed an American Diet

This study shows PFOA affects lipid levels in hPPAR mice on an American diet, with context-dependent effects on liver and serum triglycerides.

Application of Generalized Concentration Addition to Predict Mixture Effects of Glucocorticoid Receptor Ligands

This study applies generalized concentration addition (GCA) to predict mixture effects of glucocorticoid receptor ligands, showing improved accuracy compared to other models.

Predicting the activation of the androgen receptor by mixtures of ligands using Generalized Concentration Addition

This study develops Generalized Concentration Addition (GCA) to predict the activity of androgen receptor ligand mixtures, showing it outperforms traditional methods.

Triphenyl phosphate is a selective PPARγ modulator that does not induce brite adipogenesis in vitro and in vivo

Spatiotemporal trends in polychlorinated biphenyl concentrations in seafood based on long-term monitoring and remediation in New Bedford Harbor, Massachusetts

The paper evaluates PCB concentration trends in seafood from New Bedford Harbor over time and space to assess environmental quality and human health risks.

Tributyltin induces a transcriptional response without a brite adipocyte signature in adipocyte models

This study shows that tributyltin, an environmental PPARγ ligand, induces adipogenesis but lacks the ability to promote mitochondrial biogenesis or brite adipocyte features compared to rosiglitazone.