J. Kaneshiro

Estimation of crossbridge-state during cardiomyocyte beating using second harmonic generation

This paper develops a method to estimate crossbridge-state in cardiomyocytes using SHG polarization, showing its applicability in assessing myosin force generation and drug effects.

Second harmonic generation polarization microscopy as a tool for protein structure analysis

This paper demonstrates the use of SHG polarization microscopy to detect protein conformational changes in macromolecular assemblies without labeling.