Author

Y. Asano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Chang· 3 shared M. R. Clark· 3 shared K. Ko· 2 shared M. Veselits· 2 shared R. Abraham· 2 shared A. J. Kinloch· 1 shared A. Khan· 1 shared A. Kinloch· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersImmunology

A. Chang

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Author profile →

4 papers

Recent·Most cited

Estimation of crossbridge-state during cardiomyocyte beating using second harmonic generation

T. M. Watanabe, H. Fujita, J. Kaneshiro, M. Takeda, K. Sasaki, R. Yamamoto, D. Umetsu, E. Kuranaga, S. Higo, T. Kondo, Y. Asano, Y. Sakata, S. Miyagawa

This paper develops a method to estimate crossbridge-state in cardiomyocytes using SHG polarization, showing its applicability in assessing myosin force generation and drug effects.

bioRxiv · Oct 13, 2022Biophysics

In lupus nephritis, specific in situ inflammatory states are associated with refractory disease and progression to renal failure

R. Abraham, M. S. Durkee, J. Ai, M. Veselits, G. Casella, Y. Asano, A. Chang, K. Ko, C. Oshinsky, E. Peninger, M. Giger, M. R. Clark

Using deep machine learning to analyze confocal microscopy data, the study shows CD4-T cell populations in lupus nephritis organize into spatial neighborhoods predicting renal failure progression.

bioRxiv · Sep 3, 2021 · PreprintImmunology

Intrarenal B cells integrate in situ innate and adaptive immunity in human renal allograft rejection

Y. Asano, J. Daccache, D. Jain, K. Ko, A. Kinloch, M. Veselits, D. Wolfgeher, A. Chang, M. Josephson, P. Cunningham, A. Tambur, A. Khan, S. Pillai, A. S. Chong, M. R. Clark

The paper identifies a unique B cell subset in renal allograft rejection that contributes to local inflammation through self-reactive antibodies and innate-like signaling.

bioRxiv · Sep 26, 2020 · PreprintImmunology

In situ humoral selection in human lupus tubulointerstitial inflammation

A. J. Kinloch, Y. Asano, A. Mohsin, C. J. Henry, R. Abraham, A. Chang, C. Labno, P. C. Wilson, M. R. Clark

The paper shows that anti-vimentin antibodies in lupus nephritis undergo in situ selection for enhanced binding and specificity to vimentin fibrils, challenging the notion of affinity maturation as a non-specific consequence of polyreactivity.

bioRxiv · Jun 29, 2020 · PreprintImmunology