The basis of a more contagious 501Y.V1 variant of SARS-COV-2
G. Zhang, H. Liu, Q. Zhang, P. Wei, Z. Chen, K. Aviszus, J. Yang, W. Downing, S. Peterson, C. Jiang, B. Liang, L. Reynoso, G. Downey, S. Frankel, J. Kapper, P. Marrack
This paper investigates the increased transmissibility of the SARS-CoV-2 501Y.V1 variant due to the N501Y mutation in the Spike protein's RBD and its impact on ACE2 binding and vaccine efficacy.
bioRxiv · Feb 2, 2021Biochemistry