Improving stem cell-derived pancreatic islets using single-cell multiome-inferred regulomes
H. Zhu, G. Wang, K.-V. Nguyen-Ngoc, D. Kim, M. Miller, G. Goss, J. Kovsky, A. R. Harrington, D. Saunders, R. Melton, A. C. Powers, S. Preissl, F. M. Spagnoli, K. J. Gaulton, M. Sander
The paper analyzes single-cell data to understand gene regulation in stem cell-derived pancreatic islets and identifies factors affecting beta-cell maturation and proliferation.
bioRxiv · Sep 25, 2022 · PreprintCell Biology