Author

J. L. Bose

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Kaiser· 1 shared A. Munivar· 1 shared A. Tikhonov· 1 shared A. W. Fenton· 1 shared B. D. Freudenthal· 1 shared B. J. Ryan· 1 shared C. L. Bird· 1 shared C. Menjivar· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMicrobiology

A. Kaiser

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular basis for the activation of the Fatty Acid Kinase complex of Staphylococcus aureus

M. J. Myers, Z. Xu, B. J. Ryan, Z. R. DeMars, M. J. Ridder, D. K. Johnson, C. N. Krute, T. S. Flynn, M. M. Kashipathy, K. P. Battaile, N. J. Schnicker, S. Lovell, B. D. Freudenthal, J. L. Bose

This study investigates the structure and function of the Fatty Acid Kinase complex in Staphylococcus aureus using modeling, biochemical, and cell-based approaches, revealing key residues and interactions essential for its activity.

bioRxiv · Mar 19, 2024 · PreprintMicrobiology

Fructose-1-kinase has pleiotropic roles in Escherichia coli

C. Weeramange, C. Menjivar, P. T. O'Neil, S. El Qaidi, K. S. Harrison, S. Meinhardt, C. L. Bird, S. Sreenivasan, A. W. Fenton, P. S. Hefty, P. R. Hardwidge, J. L. Bose, L. Swint-Kruse

This study shows that fructose-1-kinase in E. coli can reverse its reaction to generate F-1-P from F-1,6-BP, binds Cra, and influences metabolism and biofilm formation beyond fructose catabolism.

bioRxiv · Dec 14, 2023 · PreprintMicrobiology

Controlling the Growth of the Skin Commensal Staphylococcus epidermidis Using D-Alanine Auxotrophy

T. M. Whitfill, D. Dodds, J. L. Bose, M.-D. Dong, G. Dube, T. Grossman, A. Kaiser, K. Kulkarni, R. Leger, S. Mootien-Boyd, A. Munivar, J. Oh, M. Pestrak, K. Rajpura, A. Tikhonov, T. Turecek

This paper engineers a D-alanine auxotrophic strain of S. epidermidis that can be controlled for therapeutic use on the skin without antibiotics or resistance genes.

bioRxiv · Mar 10, 2020Microbiology