ImmunologybioRxivPreprint
Sialic acid ligands of CD28 block co-stimulation of T cells
L. J. Edgar, A. J. Thompson, V. F. Vartabedian…·J. C. Paulson
The paper shows sialic acid ligands on T cells and APCs block CD28 co-stimulation, reducing T cell activation and enhancing effector function when sialic acids are removed.
DOI 10.1101/2021.02.22.432333