Active growth signalling promotes cancer cell sensitivity to the CDK7 inhibitor ICEC0942
G. Wilson, G. Sava, K. Vuina, C. Huard, L. Meneguello, J. Coulombe-Huntington, T. Bertomeu, R. Maizels, J. Lauring, M. Tyers, S. Ali, C. Bertoli, R. A. M. de Bruin
This study identifies active mTOR signaling and cell growth as predictors of cancer cell sensitivity to the CDK7 inhibitor ICEC0942.
bioRxiv · Sep 10, 2021 · PreprintCancer Biology