R. Maizels

This study identifies that PGE2-EP2 signaling suppresses lung ILC2 responses and eosinophilic inflammation, while EP4 agonism restricts these responses, offering potential therapeutic targets for asthma and NERD.

This study identifies active mTOR signaling and cell growth as predictors of cancer cell sensitivity to the CDK7 inhibitor ICEC0942.

This paper identifies the receptor binding sites of the parasitic TGF-β mimic Hp-TGM using biophysical methods, showing it binds to TβRI and TβRII through specific domains.

The paper investigates how cytokines regulate intestinal epithelial responses through developmental pathways, showing IL-13 induces goblet cells via NOTCH signaling and uses BMP signaling as a feedback loop in tuft cell hyperplasia.