G. Wilson

Emergence of a senescent and inflammatory pulmonary CD4+ T cell population prior to lung allograft failure

The paper identifies CD4+CD57+PD1+ T cells in lung transplant recipients that predict allograft dysfunction and are associated with fibrosis in both human and mouse models.

3D Reconstruction of Murine Mitochondria Exhibits Changes in Structure Across Aging Linked to the MICOS Complex

This study examines age-related changes in mitochondrial 3D structure in mouse muscle and heart tissues, linking these changes to the MICOS complex and metabolic alterations.

Active growth signalling promotes cancer cell sensitivity to the CDK7 inhibitor ICEC0942

This study identifies active mTOR signaling and cell growth as predictors of cancer cell sensitivity to the CDK7 inhibitor ICEC0942.

Interferon-stimulated and metallothionein-expressing macrophages are associated with acute and chronic allograft dysfunction after lung transplantation

The paper identifies two macrophage subsets in lung transplant recipients associated with acute and chronic allograft dysfunction using single-cell RNA sequencing.

Leishmania infantum xenodiagnosis from vertically infected dogs reveals significant skin tropism

This study shows vertically infected dogs transmit Leishmania infantum to sand flies more effectively when they have moderate disease, with higher skin parasite loads correlating strongly with sand fly infection.

Voltage-Gated Potassium Channel Kv1.3 as a Therapeutic Target for Pancreatic Ductal Adenocarcinoma

This study shows Kv1.3 is highly expressed in human PDAC and novel Kv1.3 inhibitors combined with chemotherapy significantly reduce tumor growth in mouse models.

Genetic variation at the species and population levels in the Rocky Mountain ridged mussel (Gonidea angulata)

This study examines genetic variation in Gonidea angulata, finding limited mitochondrial haplotypes and distinct microsatellite patterns across populations, with low inbreeding and conservation concerns.

Estimating Wildlife Vaccination Coverage Using Genetic Methods

This study estimates vaccine coverage in European badgers using genetic methods, finding 44-65% vaccinated in one year and 70-85% over four years.