Author

C. Bertoli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:genetic perturbation / CRISPR· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

R. A. M. de Bruin· 4 shared K. Kiso· 2 shared L. Meneguello· 2 shared A. T. Olson· 1 shared C. Huard· 1 shared C. K. Martin· 1 shared G. Sava· 1 shared G. Wilson· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersCancer Biology

R. A. M. de Bruin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Oncogenic c-Myc activity increases tolerance to proteotoxic and genotoxic stress through regulation of HSF1

J. Jones, K. Kiso, C. Bertoli, R. A. M. de Bruin

This study shows c-Myc increases cellular tolerance to proteotoxic and genotoxic stress by upregulating HSF1, which supports cell survival under c-Myc-induced stress conditions.

bioRxiv · Feb 2, 2022 · PreprintCancer Biology

Active growth signalling promotes cancer cell sensitivity to the CDK7 inhibitor ICEC0942

G. Wilson, G. Sava, K. Vuina, C. Huard, L. Meneguello, J. Coulombe-Huntington, T. Bertomeu, R. Maizels, J. Lauring, M. Tyers, S. Ali, C. Bertoli, R. A. M. de Bruin

This study identifies active mTOR signaling and cell growth as predictors of cancer cell sensitivity to the CDK7 inhibitor ICEC0942.

bioRxiv · Sep 10, 2021 · PreprintCancer Biology

Oncogenic c-Myc induces replication stress by increasing cohesins chromatin occupancy

S. Peripolli, T. Singh, H. Patel, L. Meneguello, K. Kiso, P. H. Thorpe, C. Bertoli, R. A. M. de Bruin

This study identifies a novel mechanism by which c-Myc induces replication stress through increased chromatin-bound cohesins in the G1 phase.

bioRxiv · Jul 25, 2021 · PreprintCancer Biology

Vaccinia Virus Arrests and Shifts the Cell Cycle

C. K. Martin, J. Samolej, A. T. Olson, C. Bertoli, M. S. Wiebe, R. A. M. de Bruin, J. Mercer

This study investigates how vaccinia virus affects host cell cycle progression and proliferation, identifying viral effectors responsible for cell cycle inhibition and shift.

bioRxiv · Jul 19, 2021Microbiology