Author

J. Leu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

J. Kendall· 2 shared J. M. Sheltzer· 2 shared N. K. Chunduri· 2 shared Z. Storchova· 2 shared Z. Wang· 2 shared A. Vasudevan· 1 shared D. A. Lukow· 1 shared D. Levy· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

J. Kendall

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2 papers

Recent·Most cited

Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies

D. A. Lukow, E. L. Sausville, P. Suri, N. K. Chunduri, J. Leu, J. Kendall, Z. Wang, Z. Storchova, J. M. Sheltzer

This study shows that chromosomal instability accelerates cancer cell adaptation to anti-cancer therapies by enabling specific aneuploidy events that reduce drug sensitivity.

bioRxiv · Sep 25, 2020Cancer Biology

Single chromosome gains can function as metastasis suppressors and metastasis promoters

A. Vasudevan, P. S. Baruah, J. C. Smith, Z. Wang, N. M. Sayles, P. Andrews, J. Kendall, J. Leu, N. K. Chunduri, D. Levy, M. Wigler, Z. Storchova, J. M. Sheltzer

The paper investigates how single chromosome gains can either suppress or promote metastasis in cancer, showing that specific aneuploidies are linked to distinct clinical outcomes.

bioRxiv · Oct 10, 2019Cancer Biology