Single chromosome gains can function as metastasis suppressors and metastasis promoters
A. Vasudevan, P. S. Baruah, J. C. Smith, Z. Wang, N. M. Sayles, P. Andrews, J. Kendall, J. Leu, N. K. Chunduri, D. Levy, M. Wigler, Z. Storchova, J. M. Sheltzer
The paper investigates how single chromosome gains can either suppress or promote metastasis in cancer, showing that specific aneuploidies are linked to distinct clinical outcomes.
bioRxiv · Oct 10, 2019Cancer Biology