Cancer BiologybioRxivPreprint
Epigenetic reprogramming of plasmacytoid dendritic cells drives type I interferon-dependent differentiation of acute myeloid leukemias for therapeutic benefit
J. Salmon, I. Todorovski, S. J. Vervoort…·R. W. Johnstone
The paper shows that inhibiting HDACs in AML promotes type I IFN production by pDCs, enhancing anti-tumor immunity and therapeutic benefit.
DOI 10.1101/2020.08.23.235499