MicrobiologybioRxiv
Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance
M. Fareh, W. Zhao, W. Hu…·J. A. Trapani
This study reprograms CRISPR-Cas13b to suppress SARS-CoV-2 replication and resist viral mutations by tolerating single-nucleotide mismatches.
DOI 10.1038/s41467-021-24577-9