J. M. Craig

The paper uses nanopore sequencing to study the single-nucleotide kinetics of a reverse transcriptase, revealing its ability to sense and destabilize RNA structures during cDNA synthesis.

This study uses nanopore tweezers to analyze SARS-CoV-2 helicase nsp13 motion and inhibition at single-nucleotide resolution, revealing kinetic mechanisms and inhibitor effects.

This study uses SPRNT to analyze how DNA sequence affects PcrA helicase kinetics during translocation and unwinding at single-nucleotide resolution.

This study uses Nanopore Tweezers to measure RecQ helicase conformational changes, revealing an asymmetric energy landscape that allows it to maintain speed against opposing forces.

This study examines the supragingival plaque microbiome in children to link microbial diversity and function to caries, identifying key metabolic pathways and novel microbes associated with disease.