Author

J. M. Munck

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Shah· 1 shared C. Latimer· 1 shared C. McCann· 1 shared D. B. Longley· 1 shared E. M. Kerr· 1 shared J. Fox· 1 shared K. J. Stott· 1 shared M. Lawler· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Shah

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1 paper

Recent·Most cited

Cancer BiologybioRxivNov 20, 2020

Clinical positioning of the IAP antagonist tolinapant (ASTX660) in colorectal cancer

D. B. Longley, N. T. Crawford, K. J. Stott…·V. M. Coyle

This study shows tolinapant, an IAP inhibitor, enhances chemotherapy-induced apoptosis in colorectal cancer by modulating FLIP and HDACs, suggesting its clinical use in poor prognosis MSS CRC with elevated cIAP1/2.

DOI 10.1158/1535-7163.mct-20-1050

humanproteomics

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