Cancer BiologybioRxiv
Single cell dissection of developmental origins and transcriptional heterogeneity in B-cell acute lymphoblastic leukemia
I. Iacobucci, A. G. X. Zeng, Q. Gao…·C. G. Mullighan
This study uses scRNA-seq to analyze B-ALL samples, revealing transcriptional heterogeneity and developmental origins, with specific subtypes associated with distinct cell populations and clinical outcomes.