Author

C. Qu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Plant Biology· 3 Bioengineering· 1 Biophysics· 1 Cell Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 7 Approach:experimental assay· 7 Approach:statistical model· 6 Organism:mouse· 5 Research Focus:gene regulatory network inference· 4 Research Focus:cell signaling & trafficking· 3 Approach:deep learning· 3 Research Focus:differential expression· 3

Frequent Co-Authors

J. Zhang· 3 shared J. Li· 2 shared N. Li· 2 shared X. Liu· 2 shared Y. Wang· 2 shared Y. Xu· 2 shared Y. Yuan· 2 shared Y. Zhao· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersCancer Biology

J. Zhang

Mutual co-authors in cluster

Author profile →

12 papers

Recent·Most cited

The Ubiquitin Ligase RBX2/SAG Regulates Mitochondrial Ubiquitination and Mitophagy

W. Wang, E. Li, J. Zou, C. Qu, J. Ayala, Y. Wen, M. S. Islam, N. L. Weintraub, D. J. Fulton, Q. Liang, J. Zhou, J. Liu, J. Li, Y. Sun, H. Su

This study identifies RBX2 as a key component of the CRL5 ubiquitin ligase that regulates mitophagy in cardiomyocytes independently of PARKIN, maintaining cardiac homeostasis.

bioRxiv · Feb 24, 2024Pathology

Efficient cloning of genes for wheat yield component traits from QTLs via sequencing of the RIL population

M. Zhang, X. Han, H. Wang, J. Sun, B. Guo, M. Gao, H. Xu, G. Zhang, H. Li, X. Cao, N. Li, Y. Xu, Q. Wu, C. Wang, G. Zhang, , S. Li

This study develops a method to clone genes for wheat yield traits by sequencing RIL populations, identifying and validating 11 candidate genes from 77 QTLs.

bioRxiv · Feb 22, 2024 · PreprintPlant Biology

Single cell dissection of developmental origins and transcriptional heterogeneity in B-cell acute lymphoblastic leukemia

I. Iacobucci, A. G. X. Zeng, Q. Gao, L. Garcia-Prat, P. Baviskar, S. Shah, A. J. Murison, V. Voisin, M. Chan-Seng-Yue, C. Cheng, C. Qu, C. Bailey, M. Lear, M. Witkowski, X. Zhou, , C. G. Mullighan

This study uses scRNA-seq to analyze B-ALL samples, revealing transcriptional heterogeneity and developmental origins, with specific subtypes associated with distinct cell populations and clinical outcomes.

bioRxiv · Dec 4, 2023Cancer Biology

Amyloplast sedimentation repolarizes LAZYs to achieve gravity sensing in plants

J. Chen, R. Yu, N. Li, Z. Deng, X. Zhang, Y. Zhao, C. Qu, Y. Yuan, Z. Pan, Y. Zhou, K. Li, J. Wang, Z. Chen, X. Wang, X. Wang, , H. Chen

This study identifies a molecular mechanism by which amyloplast sedimentation triggers LAZY protein relocalization to mediate gravity sensing in Arabidopsis.

bioRxiv · Apr 17, 2023Plant Biology

StereoSiTE: A framework to spatially and quantitatively profile the cellular neighborhood organized iTME

X. Liu, C. Qu, C. Liu, N. Zhu, H. Huang, F. Teng, C. Huang, B. Luo, X. Liu, Y. Xu, M. Xie, F. Xi, M. Li, L. Wu, Y. Li, , J. Zhang

StereoSiTE analyzes spatial transcriptomics data to identify cell-cell interactions in the tumor microenvironment and reveals neutrophil-driven communication networks in treated xenograft models.

bioRxiv · Dec 31, 2022Cancer Biology

Matrix Softening Controls Stretch-Induced Cellular Memory and Fibroblast Activation

Y. Hong, X. Peng, H. Yu, M. Jafari, D. Shakiba, Y. Huang, C. Qu, E. Melika, A. Tawadros, A. Mujahid, J. Sandler, K. Pryse, J. Sacks, E. Elson, G. Genin, F. Alisafaei

This study shows that matrix softening influences stretch-induced cellular memory and fibroblast activation, with a model predicting activation levels based on ECM properties.

bioRxiv · Oct 12, 2022 · PreprintBiophysics

SIC50: Determination of IC50 by an optimized Sobel operator and a vision transformer

Y. Wang, W. Zhang, H. Yip, C. Qu, H. Hu, X. Chen, T. Lee, X. Yang, B. Yang, P. Kumar, S. Y. Lee, J. Casimiro, J. Zhang, K. S. Lam, A. Wang

SIC50 uses a vision transformer and Sobel operator to determine IC50 from phase-contrast images, validated with four drugs and 1536-well plates.

bioRxiv · Aug 12, 2022 · PreprintBioengineering

Two Types of Cinnamoyl-CoA Reductase Function Divergently in Tissue Lignification, Phenylpropanoids Flux Control, and Inter-pathway Cross-talk with Glucosinolates as Revealed in Brassica napus

N. Yin, B. Li, X. Liu, Y. Liang, J.-P. Lian, Y. Xue, C. Qu, K. Lu, L. Wei, R. Wang, J. Li, Y.-R. Chai

This study identifies and characterizes two divergent CCR subfamilies in Brassica napus, revealing their distinct roles in lignin biosynthesis, phenylpropanoid flux, and glucosinolate interactions.

bioRxiv · Mar 1, 2021 · PreprintPlant Biology

Response of whitefly to the wild tomato Solanum habrochaites

F. Li, Y. Dewer, J. Tian, D. Li, C. Qu, C. Luo

This study examines how the wild tomato Solanum habrochaites affects the survival, fecundity, and gene expression of the whitefly Bemisia tabaci, revealing stress gene induction and potential for pest control.

bioRxiv · Feb 26, 2021Ecology

3D Visualization of the Podocyte Actin Network using Integrated Membrane Extraction, Electron Microscopy, and Deep Learning

C. Qu, R. Roth, C. Loitman, D. Hammad, G. M. Genin, J. H. Miner, H. Y. Suleiman

This paper develops a new visualization technique to study 3D actin networks in podocytes, revealing structural changes in healthy and injured states.

bioRxiv · Jan 29, 2021 · PreprintCell Biology

High expression of JAM2 indicates better prognosis and immunotherapy response in breast cancer

Y. Peng, C. Qu, Y. Zhang, B. Zong, Y. Fu, J. Xie, S. Liu

This study identifies JAM2 as a prognostic marker and potential predictor of immunotherapy response in breast cancer using multi-database analysis.

bioRxiv · Dec 11, 2020 · PreprintCancer Biology

N-Acetyl Cysteine Alleviates Coxsackievirus B-Induced Myocarditis by Suppressing caspase-1

Y. Wang, S. Zhao, Y. Chen, Y. Wang, T. Wang, X. Wo, Y. Dong, J. Zhang, W. Xu, C. Qu, X. Feng, X. Wu, Y. Wang, Z. Zhong, W. Zhao

This study shows N-acetyl cysteine (NAC) alleviates Coxsackievirus B-induced myocarditis by inhibiting caspase-1 and viral proteases, offering a potential therapeutic option.

bioRxiv · Aug 12, 2019 · PreprintMicrobiology