Cancer BiologybioRxiv
Inflammatory Recruitment of Healthy Hematopoietic Stem and Progenitor Cells in the Acute Myeloid Leukemia Niche
D.-W. Chen, J.-M. Fan, J. M. Schrey…·P. Kurre
This study shows that healthy hematopoietic stem and progenitor cells (HSPCs) adopt inflammatory gene expression programs in the AML niche, driven by AML-derived extracellular vesicles.